Another study, by M. Deghrigue et al. (2013), found that while black tea kombucha was effective aganst one of two types of human lung cancer cells, green tea kombucha was more effective against both in Vitro. While the researchers weren’t sure by what mechanism the anti-cancer properties were achieved, attributing it potentially to polyphenols and other antioxidants, others have speculated that it could be due to metabolites (e.g., alcohol, organic acids, vitamins, amino acids) produced by the symbiosis of the bacteria and yeast.
Other elements of kombucha that have chemopreventive or anti-tumor properties are butyric acid, oxalic acid, 4-ethylphenol, saccharic acid, heparin, antioxidants, and catechins. Polyphenols present in tea are also generally recognized to have cancer-inhibition properties, and kombucha’s effectiveness could be linked to not only those polyphenols but also other elements that appear after they are fermented.
Related studies: Cetojevic-Simin, D. D., G. M. Bogdanovic, D. D. Cvetkovic, and A. S. Velicanski. Antiproliferative and antimicrobial activity of traditional kombucha and Satureja montana L. kombucha. Journal of the Balkan Union of Oncology 13, no. 3 (2008):395-401. Deghrigue, Monia, Jihene Chriaa, Houda Battikh, Kawther Abid, and Amina Bakhrouf. Antiproliferative and antimicrobial activ- ities of kombucha tea. African Journal of Microbiology Research 7, no. 27 (2013): 3466-70. Jayabalan, Rasu. Effect of solvent fractions of kombucha tea on viability and invasive- ness of cancer cells- characterization of dimethyl 2-(2-hydroxy-2-methoxypropyli- dine) malonate and vitexin. Indian Journal of Biotechnology 10, (Jan. 2011), 75-82. Sriharia, Thummala, Ramachandran Arunkumar, Jagadeesan Arunakaran, and Uppala Satyanarayana. Down regulation of signaling molecules involved in angiogen of human prostate cancer cell line (Pc-3) by kombucha (lyophilized). Biomedicine & Preventive Nutrition 3, no.1 2013): 53-58.
AMELIORATING THE SIDE EFFECTS OF CHEMOTHERAPY AND RADIATIONEXPOSURE
radiation therapy in conjunction with chemotherapy. Anecdotally, people who drink kombucha while receiving chemotherap have reported reduced nausea and improved appetite, though no research has yet been done to con- firm these reports. However, some recent studies have explored how kombucha might help with deeper issues caused by radiation. he authors of the first study (Cavusoglu, 2010) injected blood cells ofhealthy humans with kom- bucha, and then exposed them to high doses of radiation.
The blood cells injected with the highest doses of kombucha demonstrated the lowest rate of aberrant metaphases “broken” DNA) and higher rates of cell proliferation. According to the study, kombucha does provide a “radioprotective effect again ionizing radiation.” It’s important to note that increased dosages of kombucha provided increased protection. The second study (Ibrahim, 2013) focused on rats that were exposed to cadmium chloride (a carcino- gen) ad gamma radiation. When they were injected with cadmium chloride or dosed with radiation (or both), rats consuming a steady diet of kombucha tea absorbed lower levels of toxins than those who were not. Daily kombucha consumption appeared to limit the effects. Related studies: Cavusoglu, K, and P. Guler. Protective effect of kombucha mushroom (KM) tea chromosomal on aberrations induced radiation by human gamma in peripheral lymphocytes in-vitro. Journal of Environmental Biology 31, no. 5 (2010): 851-56.